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apalutamide will lower the extent or impact of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a solid CYP2C19 inducer, with medications that happen to be CYP2C19 substrates can result in lessen publicity to these prescription drugs.Use VALTOCO precisely as your Health care se